The difference between Freebase nicotine and Nic Salts lies in their chemical structure and how they affect the vaping experience. Freebase nicotine is the purest form of nicotine, with an Alkali pH level, which results in a harsher throat hit and is better suited for lower-wattage devices. On the other hand, Nicotine Salts are created by combining nicotine with other compounds, which neutralise the pH and create a smoother throat hit. This allows for higher nicotine concentrations without the harshness, making them ideal for those who want a more intense and satisfying experience, similar to that of disposable vapes.